Over on Flylady.net, they're in the middle of a "Super Fling Boogie": get rid of as much as you can in two weeks. I find getting rid of stuff and decluttering space makes life much better (we got rid of a whole carload of stuff last month), and I love hearing about how other people have cleaned out their dclutter. As an inspiration, check out the Weirdest Items Decluttered. Here's an example of some of the stuff people save:
The little metal "key" we had to use everyday to adjust the bone spreader implanted in my mouth (for 6 months) when I was twelve! I'm now thirty five!!! Why did my Mom save it? Did she think my jaw would shrink back?